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Find local businesses, view maps and get driving directions in Google Maps. As a nod to the historic site—the original Vernor’s Pharmacy—we’re proudly serving up Vernor’s Ginger Soda alongside our full collection of frames. To top it off, you can find original artwork by David Rubello just above the Reference Desk. 134 0 7 0s7 3. An optometrist is available to provide eye exams, and opticians are on hand to fit and adjust your Warby Parker frames. We can take any optical measurements needed to complete your order, and if your frames don’t fit perfectly on arrival, an optician is available for adjustments. We have a 30-day, no-questions-asked policy for returning and exchanging our eyewear.

Whether you purchased online or in-store, we can help you out. NORD gratefully acknowledges Scott Pentiuk MD, Assistant Professor of Pediatrics, Cincinnati Children’s Hospital Medical Center, and Adam Mezoff, MD, Professor of Pediatrics, Cincinnati Children’s Hospital Medical Center, for assistance in the preparation of this report. Symptoms vary greatly from case to case depending upon the exact size and location of the deleted genetic material. Common symptoms include a distinctive cry that resembles the mewing of a cat, characteristic facial features, slow growth, and microcephaly, a condition that indicates that head circumference is smaller than would be expected for an infant’s age and sex. Additional symptoms affecting different organ systems of the body can also occur. The disorder was first described in the medical literature in 1963 by doctor Lejeune who named the disorder after the distinctive cat-like cry.

The symptoms of cri du chat syndrome vary from case to case. The characteristic high-pitched, shrill cry associated with cri du chat syndrome is present during the first few weeks of life. The cry, which resembles the mewing of a cat, becomes less pronounced as affected infants grow older. As affected infants age the face may lose its plumpness and become abnormally long and narrow. Most affected infants also display some degree of psychomotor and intellectual disability. Psychomotor disability is a delay in the acquisition of skills requiring mental and muscular activities such head control, sitting up, and walking. About half of children with cri du chat syndrome were able to dress themselves by age 5 years.

Moderate to severe intellectual disability is present in most cases. Speech development is especially delayed in children with cri du chat syndrome. Affected children usually understand speech better than they can communicate. Some children may display hyperactivity or self-abusive behaviors. Affected infants may have feeding difficulties due to low muscle tone, poor suck, and gastroesophageal reflux disease.